Causes
The factors may be pre-testicular, testicular or post-testicular.
Pre-testicular: Drugs, smoking, alcohol, medications affecting spermatogenesis (spironolactone, chemotherapy).
Testicular: Age, genetic defects, carcinoma, varicocele, trauma, hydrocele, mumps, idiopathic.
Post-testicular: These defects include the defects in the genital tract and ejaculation problems.
Diagnosis
Diagnostic tools include medical history, physical examination, semen analysis, blood analysis to rule out hormonal imbalances or genetic issues. Patient’s partner can also be interviewed.
Treatment
The treatment modalities depend upon the underlying disease and extent of impairment. Pre-testicular issues can be rectified by medicines. Testicular based infertility is usually medication resistant. Post-testicular infertility can be overcome by surgery.
In infertility condition, the female fertility should also be checked.